The Brain Campus (CC) is an area managed by the Santos Dumont Institute (ISD) that has buildings dedicated to education and research in neurosciences and neuroengineering. UOne of the buildings houses the Edmond and Lily Safra International Institute of Neuroscience (IIN-ELS), where are implemented laboratories of electrophysiology, neurorehabilitation, neurobiology, neuroengineering, neuroprosthetics, computational neuroscience, human-machine interface, conventional microscopy, confocal microscopy, neurosurgery, among other areas. The building also has an auditorium and spaces for scientific meetings and exhibitions. Since March 2018 ISD's administrative headquarters are located in CC. 

The implementation of the Brain Campus was made official in a Presidential Decree of December 12, 2007. Financial resources are provided by the Ministry of Education (MEC) and the execution of the work was the responsibility of Federal University of Rio Grande do Norte (UFRN), owner of the land and buildings belonging to the Campus.

The management and responsibility for the Brain Campus rests with the ISD, through a Contract for Assignment of Use of Public Asset signed with UFRN, in May 2016, which enables the Institute to develop education, postgraduate and research activities on site.